Karamenah was an Egyptian slave girl in service of Fu Manchu, but she was freed by Sir Denis Nayland Smith, and Doctor Petrie. Karamenah fell in love with Petrie and married him.
Marvel
Years later, Karamenah was presumed dead, but in truth she was revitalized by Fu Manchu. The refined Elixir Vitae used on her not only preserved life but de-aged Karamenah. Fu Manchu then attached mind control electrodes to her head to take control of her actions. For years Karamenah was his puppet until Fah Lo Suee freed her.
Other Media
The Adventures of Dr. Fu Manchu
In the TV-series Karamenah was portrayed by actress Laurette Luez.
Karamenah was in a servant-master relationship with Fu Manchu and assisted him in his schemes.