Origin
May Reilly was a woman born during the Industrial Revolution in a different reality and made herself a steampunk spider suit with 18th century looking machinary. She started calling herself Lady Spider and tried to be a hero in her own reality.
Creation
Lady Spider was created by Robbie Thompson and Denis Medri and first appeared in Spider-Verse Vol.1 issue 1 (2015).
Major Story Arcs
Spider-Verse
May lived her life, but was eventually recruited by Spider-UK and the Spider-Army to fight against Morlun and his family. May Reilly fought bravely and even gained a few new friendships. After Morlun was defeated, May joined a number of former Spider-Army members in becoming the guardians of the great Web, also known as the Web Warriors.