Origin
Leonardo di ser Piero da Vinci was born in Vinci, Florence in 1452. The son of simple parents, Leonardo became a genius scientist and artist. Because of his polymath like interests he is often portrayed in science fiction as having knowledge and foresight well beyond that of his era.
Marvel Comics
The Marvel version of Da Vinci was created by Larry Lieber and first appeared in Tales of Suspense #49.
This version of Leonardo Da Vinci was a member of the Brotherhood of the Shield, the ancient organization behind the modern S.H.I.E.L.D.